U.S. Sens. John McCain and Jon Kyl led a group of Republican officials Wednesday denouncing a ballot measure that would allow medical marijuana.

Republican Sen. John McCain framed the porousness of America's borders as both a national security concern and a human rights issue Sunday in the only scheduled general election debate in Arizona's U.S. Senate race.

At a time when the state treasury is reeling from a multi-billion dollar deficit, jobs are scarce and many residents are losing their homes to foreclosure, Arizona’s candidates for federal office appear to be recession-proof.

A now-disbarred Florida lawyer who admitted to orchestrating a huge Ponzi scheme gave more than $180,000 to Arizona Sen. John McCain's presidential campaign, contributions that McCain's Senate rival is now making an issue in their competitive primary.