ORPHAMED INC.

APPLICATION FOR AUTHORITY TO TRANSACT BUSINESS IN ARIZONA
The name of the corporation is: ORPHAMED INC., A(n) Delaware Corporation.
[X] We are a foreign corporation applying for authority to transact business in the state of Arizona.
1. The exact name of the foreign corporation is: ORPHAMED INC. If the exact name of the foreign corporation is not available for use in this state, then the fictitious name adopted for use by the corporation in Arizona is: (blank) (FN).
2. The name of the state, province or country in which the foreign corporation is incorporated is: Delaware.
3. The foreign corporation was incorporated on the 20th day of December, 2010 and the period of its duration is: Perpetual.
4. The street address of the principal office of the foreign corporation in the state, province or country of its incorporation is: 1209 Orange Street, Wilmington, DE 19801.
5. The name and street address of the statutory agent for the foreign corporation in Arizona is: C T Corporation System, 2394 East Camelback Road, Phoenix, AZ 85016.
5.a. The street address of the known place of business of the foreign corporation in Arizona IF DIFFERENT from the street address of the statutory agent is: (blank).
5.b. General correspondence should be mailed to the address specified above in section 4 [X] or section 5a [ ].
6. The purpose of the corporation is to engage in any and all lawful business in which corporations may engage in the state, province or country under whose law the foreign corporation is incorporated, with the following limitations, if any: (blank).
7. The names and usual business addresses of the current directors and officers of the foreign corporation are: (Attach additional sheets if necessary.) SEE ATTACHED. ATTACHMENT TO APPLICATION FOR AUTHORITY TO TRANSACT BUSINESS IN ARIZONA OF ORPHAMED INC. Directors and Officers. NAME: Jonah Shacknai, TITLE: President and Chief Executive Officer, Director, BUSINESS ADDRESS: 7720 N. Dobson Road, Scottsdale, AZ 85256; Mark A. Prygocki, Sr., Executive Vice President and Chief Operating Officer, Director, 7720 N. Dobson Road, Scottsdale, AZ 85256; Jason D. Hanson, Executive Vice President and Secretary, Director, 7720 N. Dobson Road, Scottsdale, AZ 85256; Richard D. Peterson, Executive Vice President, Chief Financial Officer and Treasurer, 7720 N. Dobson Road, Scottsdale, AZ 85256.
8. The foreign corporation is authorized to issue 10,000 shares, itemized as follows: (Attach additional sheets if necessary.) 10,000 shares of Common [class or series] stock at [ ] no par value or par value of $.01 per share.
9. The foreign corporation has issued 1000 shares, itemized as follows: (Attach additional sheets if necessary.) 1000 shares of Common [class or series] stock at [ ] no par value or par value of $.01 per share.
10. The character of business the foreign corporation initially intends to conduct in Arizona is: Research development.
DATED this 4 day of January, 2011. Signature: /s/ Richard D. Peterson, EVP, CFO & Treasurer.
ACCEPTANCE OF APPOINTMENT BY STATUTORY AGENT The undersigned hereby acknowledges and accepts the appointment as statutory agent of this corporation effective this 4 day of January, 2011. C T Corporation System, /s/ James M. Halpin, Assistant Secretary.
1/21, 1/28, 2/4, 2011 editions Arizona Capitol Times